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July 1, 2024

Introduction to Exosomes and Stem Cell Technologies

Introduction to Exosomes and Stem Cell Technologies

This week on Facially Conscious, we're excited to bring you a fascinating episode with Dr. Greg Maguire, co-founder of NeoGenesis. Our focus today is on the revolutionary use of stem cell-based technologies in medicine, with a special emphasis on exosomes. These are not cells but extracellular vesicles that contain a myriad of bioactive molecules that the cells release, making them a hot topic in the medical world.

While exosomes are making waves in the beauty industry, it's crucial to understand what they are and how they work. The ability to harness exosomes for skincare is a game-changer, but it's important to tread carefully. The FDA has yet to regulate exosomes from overseas, so it's vital to be cautious when sourcing these products to ensure your safety and well-being. 

Dr. Maguire's interest in exosomes stemmed from his work with stem cells, particularly in treating brain conditions. He transitioned to studying the skin and discovered its potential in skincare.

 

Properties of Exosomes

Exosomes are a delivery system for various molecules, including growth factors, immune modulators, heat shock proteins, and antioxidants. They can target dysfunctional tissue and penetrate barriers, making them valuable in skincare and drug delivery.

 

Safety and Regulation: 

It's crucial to source exosome products from reputable companies that follow strict safety standards. Some products on the market may not contain genuine exosomes or may be derived from potentially unsafe sources.

 

Applications: 

Exosomes are not just a one-trick pony. They have a wide range of applications, from skincare to wound healing, hair loss treatment, and even inflammation mitigation. They can also be used in conjunction with medical procedures like laser treatments and surgery to speed up healing and reduce recovery time. Their versatility is truly remarkable.

 

Usage and Dosage:

 Exosome products can be used topically on the skin, with recommended dosages varying based on individual needs and conditions. It's advisable to start with higher dosages initially and then adjust based on the response.

 

Future Research and Development: 

Ongoing research aims to further understand the complex mechanisms of exosomes and their interactions with skin cells. Dr. Maguire emphasized the importance of using a combination of exosomes and soluble factors, the molecules released from the stem cells that are not contained in the exosomes, for optimal therapeutic outcomes.

 

Overall, the discussion highlighted the potential of exosome technology in skincare and medicine while emphasizing the importance of sourcing products from reputable sources and adhering to safety guidelines.

 

Join us for an in-depth exploration of this exciting and groundbreaking skincare technology in this episode of EXOSOMES IN SKINCARE with NeoGenesis founder Dr. Greg Maguire!

 

SHOW NOTES

NeoGenesis 

Exosomes

stem cell-based technology

CNS scientist 

biophysicist 

physiological renormalization

Jimmy Allison – Nobel prize winner

globular proteins

extracellular vesicles

liposomes

polysaccharides

micro channeling

microneedling

sub-Q

adipose mesenchymal stem cell

synergistically

tumorigenesis

Ames test

mutagenesis of DNA

human insult patch repeat test (HRIPT)

fibroblast

oncogenic

lyophilized exosomes

tethered proteins 

fibrosis 

anti-fibrotic

eczema

atopic dermatitis

rosacea

macrophage

T cell 

Dermal Papilla

alopecia

radiation dermatitis

ablative lasers

Dr. Peter Elias 

S2RM technology 

Rogaine 

soluble fraction